Eukaryotic DNA Polymerases in Homologous Recombination
نویسندگان
چکیده
منابع مشابه
Eukaryotic DNA Polymerases in Homologous Recombination.
Homologous recombination (HR) is a central process to ensure genomic stability in somatic cells and during meiosis. HR-associated DNA synthesis determines in large part the fidelity of the process. A number of recent studies have demonstrated that DNA synthesis during HR is conservative, less processive, and more mutagenic than replicative DNA synthesis. In this review, we describe mechanistic ...
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ژورنال
عنوان ژورنال: Annual Review of Genetics
سال: 2016
ISSN: 0066-4197,1545-2948
DOI: 10.1146/annurev-genet-120215-035243